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Results of Other Medication on VIAGRA Sildenafil metabolism is principally mediated by CYP3A4 (big route) and CYP2C9 (small route). Thus, inhibitors of such isoenzymes might lessen sildenafil clearance and inducers of these isoenzymes may possibly maximize sildenafil clearance.Sildenafil can minimize blood move towards the optic nerve of the attent